Corporate bonds

You can now issue bonds to borrow money from other corporations or investors. Set the interest rate and months to maturity to make the bond interesting to buyers.
If you have spare cash, you can buy bonds to receive a monthly interest payment.

Multiplayer

Games can now be saved (and are auto-saved). When starting a new multiplayer game, a save-game can be loaded to continue playing that game instead of starting a brand new.
The new corporate bond mechanic can be used to help out late-joining players by having cash-strong established players buy low interest bonds.
All players can now change the game speed.
The number of corporations allowed in-game has been changed to 12 so all slots can be filled by players while also having max number of AI competitors.

Scoring

Scores are now calculated based on players' ownership in corporations.
Previously a player would get a score based on his net worth and the accomplishments of the corporation he controlled as CEO. Score is now based on his ownership so if the corporation gets 50 points for dominating the Retailing industry, a player who owns 20% of that corporation will get 10 points (50 pts x 20% = 10).

Other

Investors are more active at buying and selling shares.
Tweaked interest rate and credit limit
Max CEO salary increases over time
Games can now be saved (and continued) after goals are met (or max time reached)
Frequency of petitions for bankruptcy are reduced